Hexapeptide-9 CAS NO.1228371-11-6

Hexapeptide-9 CAS NO.1228371-11-6

Hexapeptide-9  CAS  NO.1228371-11-6

Hexapeptide-9 CAS NO.1228371-11-6

Hexapeptide-9 CAS NO.1228371-11-6

Hexapeptide-9 (CAS NO. 1228371-11-6) is a synthetic, high-purity hexapeptide engineered for advanced cosmetic applications. It is designed as a specific signaling peptide that targets cellular pathways involved in skin aging, with a primary focus on improving skin firmness, elasticity, and overall structural integrity. This biomimetic peptide is used in high-performance skincare formulations to combat signs of sagging, loss of contour, and wrinkles, promoting a more lifted and youthful appearance. It is typically supplied as a lyophilized powder for incorporation into serums, creams, and other topical products.


TECHNICAL SPECIFICATIONS


Item
Specification Details
Product NameHexapeptide-9
CAS NO.1228371-11-6
AppearanceWhite to off-white lyophilized powder
Molecular FormulaC₃₀H₄₈N₁₂O₇
Molecular Weight664.78 g/mol
Amino Acid SequenceH-Gly-Gln-Pro-Arg-Gly-Leu-OH
Purity (RP-HPLC)≥ 98.0%
Solubility
Highly soluble in water; soluble in glycerin and propylene glycol.
Endotoxin<0.5 eu="">
Biological ActivityA bioactive hexapeptide that acts as a tyrosinase-inhibiting peptide (TIP), effectively reducing melanin synthesis by downregulating tyrosinase expression. It targets hyperpigmentation, age spots, and promotes an even skin tone.
Storage Conditions
Store at 2-8°C in a dry, sealed container, protected from light. Stable for 24 months under recommended conditions.
Stock LocationStock in USA
MOQ
1g


1.MECHANISM OF ACTION

Hexapeptide-9 operates through multiple pathways to optimize skin health. Its primary mechanism involves modulation of key cellular signaling pathways that regulate collagen synthesis and extracellular matrix remodeling. The peptide interacts with specific receptors on fibroblast cells, stimulating collagen I and III production while inhibiting collagen degradation enzymes. Additionally, it enhances antioxidant defense systems and supports barrier function restoration through regulation of tight junction proteins and lipid synthesis pathways.

2.APPLICATION INDUSTRIES

Anti-Aging Formulations: Targeting fine lines, wrinkles, and loss of skin elasticity in age-defying serums and creams

Skin Barrier Repair: Supporting compromised skin barrier function in sensitive, dry, or irritated skin treatments

Post-Procedure Care: Accelerating skin recovery following cosmetic procedures, laser treatments, or chemical peels
Preventive Skincare: Proactive protection against environmental stressors and premature aging in daily care productsResearch Applications: Investigation of peptide-mediated skin regeneration mechanisms and novel delivery systems

3.CLINICAL & PRECLINICAL EFFICACY

Collagen Enhancement: Demonstrated significant increase in collagen density (up to 35% improvement in preclinical models) and improved skin elasticity measurements

Barrier Function: Enhanced skin hydration parameters (TEWL reduction ≥25%) and strengthened stratum corneum integrity in controlled studies
Wrinkle Reduction: Visible reduction in wrinkle depth (average 20-30% improvement) and improved skin smoothness in consumer perception studies
Compatibility Profile: Excellent skin tolerance with minimal irritation potential, suitable for sensitive skin formulations
Formulation Stability: Maintains biological activity across wide pH ranges (4.0-8.0) and compatible with common cosmetic delivery systems

    4.Certificate

    • GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

    Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


    We prioritize:

    1.A rigorous quality management system

    2.Batch traceability and stability data

    3.Professional laboratory testing and validation

    4.Compliance with international trade standards


    Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

    5.DELIVERY & SHIPPING

    We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

    Professional and Secure Packaging

    Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

    We can also customize packaging according to customer needs.

    Shipping Methods 

    Main Method: International Air Freight

    We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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    Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

    We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


    Hot Tags: Pentapeptide-25, Anti-aging peptide, Collagen booster, Skin firming, Wrinkle reducer, Cosmetic ingredient, Peptide synthesis, Skincare, CAS 1000313-64-36, Synthetic peptide, Dermal repair, Extracellular matrix, Fibroblast activation, Topical serum, Cosmetic research, High purity peptide, Supplier, Manufacturer, Bulk order, Cosmetic raw materialResearch peptide, Pharmaceutical


    If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:852 7084 6510

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