Humanin (human) CAS NO.330936-69-1
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Humanin (human) |
| CAS NO. | 330936-69-1 |
| Appearance | White to off-white powder |
| Molecular Formula | C119H204N34O32S2 |
| Molecular Weight | 2687.19 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in water, dilute acetic acid, or PBS |
| Endotoxin | < 1 EU/mg |
| Biological Activity | Exhibits strong neuroprotective, anti-apoptotic, and cytoprotective effects; promotes cell survival under stress conditions |
| Storage Conditions | Store at -20°C, protected from light; avoid repeated freeze-thaw cycles |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Humanin exerts its effects by binding to specific receptor complexes, including the CNTFR-α/gp130/WSX-1 trimeric receptor and formylpeptide-like receptors (FPRL1/2), thereby activating intracellular signaling pathways such as JAK/STAT, AKT, and ERK1/2. This activation leads to the inhibition of pro-apoptotic proteins like Bax and tBid, preventing mitochondrial outer membrane permeabilization and subsequent caspase-dependent cell death. Additionally, it modulates mitochondrial function and reduces oxidative stress, providing a dual-layer defense against cellular damage.
2.PRODUCT INDICATIONS
This product is intended for research use in studying neurodegenerative conditions like Alzheimer’s and Parkinson’s disease, as well as metabolic disorders including type 2 diabetes and insulin resistance. It is also applied in cardiovascular research models investigating ischemia-reperfusion injury and atherosclerosis. Furthermore, it serves as a vital tool for anti-aging and longevity research, focusing on cellular resilience and protection against age-related decline.
3.CLINICAL EFFICACY OF PRODUCT
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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