Hyperoside CAS NO.482-36-0

Hyperoside CAS NO.482-36-0

Hyperoside CAS NO.482-36-0

Hyperoside CAS NO.482-36-0

Hyperoside CAS NO.482-36-0

Hyperoside is a high-purity natural flavonoid glycoside, primarily sourced from plants such as Hypericum perforatumand Crataegus pinnatifida, supplied as a yellow powder standard for advanced pharmacological research and phytochemical analysis. This compound is specifically designed for scientists investigating cardiovascular protection, neuroprotection, and anti-inflammatory mechanisms in both in vitro and in vivo models. It serves as a critical reference material for the quality control of traditional herbal medicines and is essential for researchers studying oxidative stress, ischemia-reperfusion injury, and the screening of novel therapeutic agents for chronic diseases.

TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Hyperoside
CAS NO.
482-36-0
Appearance
Light yellow to yellow crystalline powder
Molecular Formula
C21H20O12
Molecular Weight
464.38 g/mol
Purity (RP-HPLC)
≥ 98.0%
Solubility
Soluble in DMSO, Methanol, Ethanol; slightly soluble in Water
Endotoxin< 10 EU/mg
Biological Activity
Flavonol glycoside with potent anti-inflammatory, antioxidant, and cardioprotective activities; activates Nur77 receptor and inhibits NF-κB signaling pathway.
Storage Conditions
Store at -20°C, protected from light and moisture. Keep container tightly sealed.
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Hyperoside exerts its therapeutic effects through multi-target interactions, primarily by scavenging reactive oxygen species (ROS) and activating the Nrf2 signaling pathway to enhance the body's endogenous antioxidant defenses, including the upregulation of enzymes like catalase and glutathione peroxidase. It effectively inhibits the NF-κB and MAPK signaling pathways, thereby suppressing the production of pro-inflammatory cytokines such as TNF-α and IL-6, which reduces systemic inflammation and cellular damage. Additionally, the compound modulates mitochondrial function by inhibiting the PI3K/Akt/Bad/Bcl-xL pathway to prevent apoptosis and acts as a potent activator of the Nur77 receptor, which helps inhibit abnormal vascular smooth muscle cell proliferation and supports cardiovascular health.

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2.PRODUCT INDICATIONS

Hyperoside is indicated for non-clinical research and pharmaceutical development focusing on cardiovascular and neurological disorders, where it is utilized to evaluate the efficacy of cardioprotective agents against myocardial ischemia and cerebral ischemia-reperfusion injury. Researchers employ this compound to investigate the pathophysiology of neurodegenerative diseases like Alzheimer's, often using it as a benchmark for neuroprotective screening and oxidative stress management in cellular assays. Furthermore, it serves as a primary analytical standard for manufacturers developing herbal extracts and nutraceuticals, catering to professionals in drug discovery, toxicology, and the standardization of botanical products aimed at supporting heart health and metabolic function.

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3.CLINICAL EFFICACY OF PRODUCT

Hyperoside has demonstrated significant efficacy in extensive preclinical studies, showing a robust ability to reduce infarct size and improve cardiac function in animal models of myocardial ischemia by lowering lactate dehydrogenase release and inhibiting cardiomyocyte apoptosis. Experimental data confirms that the compound significantly alleviates cerebral edema and enhances cognitive function in ischemia-reperfusion models by decreasing malondialdehyde levels and restoring superoxide dismutase activity in brain tissue. Moreover, it has proven effective in ameliorating symptoms of non-alcoholic fatty liver disease (NAFLD) and exhibits notable anti-cancer properties by inducing autophagy and apoptosis in various tumor cell lines, including breast and liver cancers, establishing its broad therapeutic potential across multiple organ systems.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


HotTags:Hyperoside, Hyperin, Quercetin 3-O-galactoside, Flavonoid Glycoside, Antioxidant, Anti-inflammatory, Cardioprotective, Neuroprotective, Hypericum Perforatum, St Johns Wort, Research Standard, Phytochemical, NF-kappaB Inhibitor, Nrf2 Activator


If you have any product requirements, please send an email to:consult@huanqiukeji9.com;whatsapp:+34 686532411

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