TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Isosinensetin |
| CAS NO. | 17290-70-9 |
| Appearance | Off-white to pale yellow crystalline powder |
| Molecular Formula | C20H20O7 |
| Molecular Weight | 372.37 g/mol |
| Purity (RP-HPLC) | ≥98.0% |
| Solubility | Soluble in DMSO, methanol, ethanol; slightly soluble in water |
| Endotoxin | ≤0.5 EU/mg (for biocompatible applications) |
| Biological Activity | Antioxidant, anti-inflammatory, neuroprotective, metabolic regulation |
| Storage Conditions | Store at 2–8°C, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
Isosinensetin exerts its biological effects primarily through modulation of key signaling pathways involved in inflammation, oxidative stress, and metabolic regulation. It acts as an agonist for the human bitter taste receptor TAS2R50, triggering downstream Gβγ-mediated signaling that influences mitochondrial function, AMPK activation, and Nrf2 pathway upregulation — all critical for cellular protection and energy homeostasis. Additionally, its ability to scavenge reactive oxygen species (ROS) and inhibit pro-inflammatory mediators like NF-κB and COX-2 contributes to its neuroprotective and cardioprotective potential. These multi-target mechanisms make Isosinensetin a versatile modulator of cellular resilience, particularly relevant in age-related and stress-induced pathologies.

Isosinensetin is indicated for use in preclinical and clinical research targeting inflammatory disorders, metabolic syndrome, neurodegenerative conditions, and oxidative stress-related diseases. Its applications extend to nutraceutical development for supporting cardiovascular health, cognitive function, and anti-aging regimens. Suitable for academic researchers, pharmaceutical R&D teams, and supplement formulators, this compound is particularly valuable in designing interventions aimed at enhancing cellular repair, reducing chronic inflammation, and improving mitochondrial efficiency. Its favorable pharmacokinetic profile and low toxicity in experimental models further support its use in both in vitro and in vivo studies seeking to validate its therapeutic potential.

Emerging clinical and preclinical data suggest that Isosinensetin exhibits significant efficacy in reducing markers of systemic inflammation, improving insulin sensitivity, and protecting against oxidative damage in tissue models. In animal studies, it has demonstrated protective effects against neurodegeneration, fatty liver disease, and endothelial dysfunction — often correlating with improved biomarkers such as TNF-α, IL-6, MDA, and SOD levels. While large-scale human trials are still underway, early findings support its role as a potent adjunct in managing metabolic and age-associated disorders. Its safety profile and bioactivity across multiple organ systems position Isosinensetin as a promising candidate for future therapeutic and functional food applications.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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