Lixisenatide CAS NO.320367-13-3/827033-10-3
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Lixisenatide |
| CAS NO. | 320367-13-3/827033-10-3 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C215H347N61O65S |
| Molecular Weight | 4858.49 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in water and dilute acidic buffers; insoluble in nonpolar organic solvents |
| Endotoxin | < 0.01 EU/μg |
| Biological Activity | GLP-1 receptor agonist; enhances glucose-dependent insulin secretion, suppresses glucagon release |
| Storage Conditions | Store at 2–8°C protected from light; lyophilized form stable at room temperature if properly sealed |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Lixisenatide mimics the action of the natural incretin hormone GLP-1 by binding to and activating GLP-1 receptors. Its mechanism is characterized by a glucose-dependent stimulation of insulin secretion from pancreatic beta cells, suppression of glucagon release from alpha cells, and a significant delay in gastric emptying. The slower gastric emptying rate is a key differentiator, as it prolongs nutrient absorption and effectively blunts sharp post-meal blood sugar spikes. Additionally, by acting on central nervous system receptors, it promotes satiety, which contributes to reduced food intake. Unlike long-acting GLP-1 RAs, lixisenatide's pharmacokinetic profile is optimized for short-term, meal-related activity, providing targeted control over postprandial hyperglycemia.
2.PRODUCT INDICATIONS
Lixisenatide is indicated to improve glycemic control in adults with type 2 diabetes mellitus, specifically targeting patients whose blood sugar remains uncontrolled despite lifestyle modifications (diet and exercise) and existing oral antidiabetic therapy. It is suitable for a broad patient population, including those on metformin, sulfonylureas, thiazolidinediones, or basal insulin regimens. The product is particularly beneficial for individuals struggling with high postprandial glucose levels, as its pharmacodynamic profile is tailored to manage meal-induced hyperglycemia. It is not indicated for patients with type 1 diabetes or for the treatment of diabetic ketoacidosis, and its use in patients with severe gastrointestinal disease, such as gastroparesis, is contraindicated due to its slowing effect on gastric emptying.
3.CLINICAL EFFICACY OF PRODUCT
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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