N-acetyl semax amidate CAS NO.1265823-54-2

N-acetyl semax amidate CAS NO.1265823-54-2

N-acetyl semax amidate CAS NO.1265823-54-2

N-acetyl semax amidate CAS NO.1265823-54-2

N-acetyl semax amidate CAS NO.1265823-54-2

N-Acetyl Semax Amidate is a highly advanced synthetic peptide derivative of the original Semax, engineered through N-terminal acetylation and C-terminal amidation to achieve superior metabolic stability and enhanced bioavailability. This modification results in a compound with an extended half-life and increased resistance to enzymatic degradation, making it particularly suitable for research into sustained cognitive enhancement and neuroprotection. It is primarily utilized in laboratory settings to study mechanisms of brain-derived neurotrophic factor (BDNF) upregulation and synaptic plasticity.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
N-acetyl semax amidate
CAS NO.
1265823-54-2
Appearance
White to off-white lyophilized powder
Molecular Formula
C39H54O10N10S1
Molecular Weight
854.96  g/mol
Purity (RP-HPLC)
≥ 98.0%
Solubility

Freely soluble in water and saline

Endotoxin< 5.0 EU/mg
Biological Activity
Potent neurotrophic and nootropic peptide; enhances BDNF/NGF expression; improves synaptic plasticity and cognitive function in preclinical models
Storage Conditions
Lyophilized powder: Store at -20°C, protected from light and moisture. Reconstituted solution: Use within 7–14 days at 2–8°C
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

The primary mechanism of action for N-Acetyl Semax Amidate involves the potentiation of neurotrophic signaling pathways, specifically through the upregulation of Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF). It modulates the dopaminergic and serotonergic systems in the central nervous system, enhancing neurotransmitter release and receptor sensitivity without acting as a direct agonist. This dual-action approach supports neuronal survival, promotes synaptic plasticity, and facilitates improved neural communication, which underlies its nootropic and neurorestorative properties.

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2.PRODUCT INDICATIONS

This product is indicated for research applications focused on cognitive enhancement, neuroprotection, and recovery from neurological stress. It is particularly relevant for studies investigating memory consolidation, attention span improvement, and resistance to mental fatigue. The enhanced stability profile of the amidate form makes it a preferred tool for long-term in vitro and in vivo studies requiring consistent peptide activity, especially in models of ischemic injury, neurodegenerative conditions, and cognitive decline.

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3.CLINICAL EFFICACY OF PRODUCT

Clinical and preclinical data derived from studies on its parent compound, Semax, demonstrate significant efficacy in improving cognitive function in subjects with mental fatigue and mild cognitive impairment. Human trials have shown rapid onset of action, with improvements in memory accuracy and attention observed within 15-30 minutes of administration. In stroke recovery models, it has been associated with accelerated functional rehabilitation and increased BDNF levels, supporting its role in promoting neuronal repair and reducing inflammation in the central nervous system.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot Tags: NASemaxAmidate, NootropicPeptide, CognitiveEnhancer, BrainHealth, BDNF, Neuroprotection, Biohacking, PeptideResearch, MentalClarity, Neuroplasticity, Supplier, Manufacturer, Bulk order,  Pharmaceutical.


If you have any product requirements, please send an email to:info@huanqiukeji9.com;whatsapp:85246842553

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