Neurokinin B CAS NO.86933-75-7
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Neurokinin B |
| CAS NO. | 86933-75-7 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C55H79N13O14S2 |
| Amino Acid Sequence | H‑Asp‑Met‑His‑Asp‑Phe‑Phe‑Val‑Gly‑Leu‑Met‑NH₂ |
| Molecular Weight | 1210.45g/mol |
| Purity (RP-HPLC) | ≥97.0% (typical commercial grade) |
| Solubility | Soluble in water, 0.1 M acetic acid, or PBS (pH 7.0‑7.4) |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Tachykinin neuropeptide; binds preferentially to the NK₃ receptor, involved in the regulation of gonadotropin release, pain transmission, and smooth muscle contraction. |
| Storage Conditions | Store at –20 °C, protected from light and moisture. For long‑term storage, recommend –80 °C. |
| Stock Location | Stock in USA |
| MOQ | 1mg |
1.MECHANISM OF ACTION
Neurokinin B functions primarily by binding to and activating the neurokinin‑3 (NK₃) receptor. This receptor interaction triggers intracellular signaling cascades, influencing the release of gonadotropin‑releasing hormone (GnRH) and other neuroendocrine modulators, thereby playing a key role in the regulation of reproductive and hormonal pathways.
2.PRODUCT INDICATIONS
This peptide is employed in research on reproductive disorders, neuroendocrine regulation, and hormonal feedback mechanisms. It is also applied in studies investigating conditions such as polycystic ovary syndrome (PCOS), hypothalamic amenorrhea, and other disorders linked to GnRH and gonadotropin secretion.
3.CLINICAL EFFICACY OF PRODUCT
Preclinical and clinical data indicate that Neurokinin B modulates GnRH pulse generation and gonadotropin release, supporting its potential as a therapeutic target in reproductive endocrinology. Its role in regulating the hypothalamic‑pituitary‑gonadal axis highlights its relevance for developing treatments for fertility and hormone‑related conditions.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
