Neuropeptide Y, human, rat CAS NO.90880-35-6
Neuropeptide Y, human, rat CAS NO.90880-35-6
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Neuropeptide Y, human, rat |
| CAS NO. | 90880-35-6 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C189H285N55O57S |
| Molecular Weight | 4271.7g/mol |
| Purity (RP-HPLC) | ≥ 95.0% |
| Solubility | Soluble in water, dilute acetic acid (e.g., 0.1% v/v), or phosphate-buffered saline (PBS). It is recommended to first dissolve in a small volume of 0.1% acetic acid or sterile water to prepare a 0.1–1.0 mg/mL stock solution, then dilute with the desired assay buffer. |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Neuropeptide Y (NPY) is a potent 36-amino acid neuropeptide that acts as a high-affinity agonist at Y1, Y2, Y4, Y5, and Y6 receptors (Y1R, Y2R, etc.). It is one of the most abundant and conserved neuropeptides in the central and peripheral nervous systems, involved in regulating energy homeostasis, appetite stimulation, anxiety, stress response, vasoconstriction, and memory processing. Biological activity is typically confirmed by receptor-binding assays (e.g., competitive binding to Y1R) or functional assays (e.g., cAMP inhibition in Y1R-expressing cells). |
| Storage Conditions | Lyophilized powder: Store desiccated at –20°C or below, protected from light, for long-term stability. Reconstituted solution: Aliquot and store at ≤ –20°C; avoid repeated freeze-thaw cycles. For extended stability, store at –80°C. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Neuropeptide Y exerts its effects by binding with high affinity to G protein-coupled Y receptors (Y1, Y2, Y4, Y5, Y6), primarily coupling to Gi/o proteins to inhibit adenylate cyclase and reduce intracellular cAMP levels. This activation leads to modulation of calcium and potassium channels, resulting in diverse physiological responses including appetite stimulation, vasoconstriction, and anxiolytic effects. The peptide's conserved structure allows for potent activation across multiple receptor subtypes, with its amidated C-terminus being critical for receptor recognition and signaling efficacy in both human and rodent systems.
2.PRODUCT INDICATIONS
This NPY peptide is indicated exclusively for research applications investigating neuropeptide Y signaling pathways in human and rodent models. It is employed in receptor binding studies, functional assays measuring cAMP inhibition, appetite regulation research, cardiovascular physiology experiments, and anxiety/stress response investigations. The product serves as a reference agonist for validating Y receptor expression, screening receptor antagonists, and studying NPY's role in metabolic disorders and neurological conditions. It is not intended for diagnostic, therapeutic, or clinical use in humans or animals.
3.CLINICAL EFFICACY OF PRODUCT
As a research reagent, Neuropeptide Y, human, rat has no established clinical efficacy or safety profile for therapeutic applications. The peptide has not undergone clinical trials, regulatory approval, or safety evaluation for any medical indication. While it contributes to fundamental understanding of NPY biology and may inform therapeutic strategies targeting Y receptors for obesity, anxiety, or cardiovascular disorders, its utility remains confined to laboratory research. Any clinical translation would require development of entirely distinct therapeutic agents with comprehensive preclinical and clinical testing.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Nov 05, 26
Global Market Analysis and Oxandrolone 50mg Price Guide
For B2B pharmaceutical buyers and researchers, understanding the oxandrolone 50mg price involves analyzing more than just a numerical value; it requires a comprehensive look at API purity, synthesis methods, and global supply chain stability. As a specialized anabolic steroid derivative, the cost is heavily influenced by the quality of raw materials and the rigor of the laboratory testing involved in the production process. This article explores the economic and technical variables that dictate market pricing for this specific compound. In the context of the global API market, pricing volatility is often tied to regulatory shifts in key manufacturing hubs
Nov 04, 26
How to Select High Purity Alisol C CAS 30489271 for Laboratory Research
High Purity Alisol C CAS 30489271 is suited to laboratories using Alisol C as a triterpenoid reference standard in metabolic, hepatology, pharmacology, HPLC/MS, botanical-extract, or selected cell-line research. We explain the application fit and the identity, purity, physical form, solvent, endotoxin, storage, quantity, and batch-record checks to make before ordering.
Nov 02, 26
Reliable Oxandrolone Supplier for High Purity Pharmaceutical APIs
When sourcing high-purity pharmaceutical ingredients for endocrine or cardiovascular research, the reliability of the supply chain is as critical as the chemical purity itself. For laboratories and manufacturers seeking a dependable oxandrolone supplier, the focus must extend beyond simple certificates of analysis to encompass consistent batch-to-batch stability and strict adherence to GMP standards. Whether the requirement is for small-scale pilot studies or large-scale industrial production, the ability to trace materials from raw synthesis to final lyophilized powder ensures the integrity of the resulting clinical or research data.