TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Neurotensin (Frog) |
| CAS NO. | / |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C70H115N23O17 |
| Molecular Weight | 1550.84/mol |
| Purity (RP-HPLC) | ≥95% |
| Solubility | Soluble in water (up to 5 mg/mL), dilute acetic acid, or DMSO |
| Endotoxin | ≤1.0 EU/mg |
| Biological Activity | Potent agonist of neurotensin receptors (NTS1 and NTS2). Modulates central nervous system function, pain perception, and dopamine signaling |
| Storage Conditions | Store desiccated at -20°C to -80°C; avoid repeated freeze-thaw cycles. Stable for 2–3 years under proper storage. |
| Stock Location | Stock in USA |
| MOQ | 1g |
Similar to its mammalian counterpart, Frog Neurotensin is believed to exert its biological effects by activating neurotensin receptors (primarily NTS1 and NTS2), which are G protein-coupled receptors. Upon binding, it likely initiates signaling cascades involving phospholipase C (PLC) activation, leading to the production of inositol trisphosphate (IP3) and diacylglycerol (DAG), resulting in intracellular calcium mobilization and protein kinase C (PKC) activation.
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