Name: OVA (323-339) CAS 92915-79-2 - High Purity for Research Use
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OVA(323-339) CAS NO.92915-79-2

OVA(323-339) is a 17-amino acid peptide fragment corresponding to residues 323-339 of chicken ovalbumin, widely recognized as a canonical T-helper cell epitope. This high-purity lyophilized peptide is primarily used as a standard antigen in immunological research to stimulate and study CD4+ T-cell responses, serving as a fundamental tool in vaccine development, immune tolerance studies, and basic immunology due to its well-defined MHC class II presentation.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	OVA(323-339)
CAS NO.	92915-79-2
Appearance	White to off-white lyophilized powder
Molecular Formula	C74H120N26O25
Molecular Weight	1773.9 g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, phosphate‑buffered saline (PBS), or dilute aqueous solutions. Recommended to dissolve in sterile water to prepare a 0.1–1.0 mg/mL stock solution.
Endotoxin	< 1.0 EU/mg
Biological Activity	OVA(323‑339) is a well‑defined T‑helper (CD4⁺) epitope derived from chicken ovalbumin. It is widely used in immunological research to stimulate ovalbumin‑specific T‑cell responses, study antigen presentation via MHC class II, and induce experimental models of T‑cell‑mediated immunity.
Storage Conditions	Lyophilized powder: Store desiccated at –20 °C or below, protected from light, for long‑term stability. Reconstituted solution: Aliquot and store at ≤ –20 °C; avoid repeated freeze‑thaw cycles.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

The peptide functions as a T-cell epitope; it is processed by antigen-presenting cells, loaded onto MHC class II molecules, and presented to CD4+ T-helper cells. This presentation engages specific T-cell receptors, leading to T-cell activation, clonal expansion, and the secretion of cytokines. This process models adaptive immune responses and is instrumental for dissecting antigen presentation pathways and T-cell activation mechanisms.

2.PRODUCT INDICATIONS

OVA(323-339) is indicated for research use in immunology, specifically for in vitro and in vivo studies of T-cell activation, proliferation assays, cytokine profiling, and immune tolerance. It is employed in mouse models to study adaptive immunity, evaluate vaccine adjuvants, and investigate autoimmune or inflammatory diseases where a well-characterized antigenic trigger is required.

3.CLINICAL EFFICACY OF PRODUCT

As a research-grade immunological tool, OVA(323-339) has no direct clinical efficacy for human therapy. Its significance lies in preclinical research, where it is essential for validating immunological concepts, testing vaccine platforms, and studying disease mechanisms. Data generated using this peptide underpins the development of immunotherapies and vaccines, but the peptide itself is not a therapeutic agent.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
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Shipping Methods
Main Method: International Air Freight

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