Name: High-Purity Ovalbumin(257-264) Antigen Peptide CAS 138831-86-4
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Ovalbumin(257-264) antigen peptide CAS NO.138831-86-4

Ovalbumin(257-264) antigen peptide is a synthetic eight-amino acid peptide derived from chicken ovalbumin, serving as a well-characterized MHC class I-restricted CD8⁺ T-cell epitope. This high-purity research-grade antigen is essential for studying cytotoxic T-lymphocyte (CTL) responses, antigen presentation, and T-cell-mediated immunity, making it a standard tool in immunological and cancer immunotherapy research.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Ovalbumin(257-264) antigen peptide
CAS NO.	138831-86-4
Appearance	White to off-white lyophilized powder
Molecular Formula	C45H74N10O13
Molecular Weight	963.2 g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, phosphate‑buffered saline (PBS), or dilute aqueous solutions. Recommended to dissolve in sterile water to prepare a 0.1–1.0 mg/mL stock solution.
Endotoxin	< 1.0 EU/mg
Biological Activity	Ovalbumin(257‑264) is a well‑defined MHC class I‑restricted CD8⁺ T‑cell epitope widely used in immunological research. It stimulates cytotoxic T‑lymphocyte (CTL) responses in H‑2Kᵇ‑restricted mouse models (e.g., C57BL/6), making it a standard tool for studying antigen‑specific CD8⁺ T‑cell activation, vaccine development, and tumor immunotherapy.
Storage Conditions	Lyophilized powder: Store desiccated at –20 °C or below, protected from light, for long‑term stability. Reconstituted solution: Aliquot and store at ≤ –20 °C; avoid repeated freeze‑thaw cycles.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

The peptide is processed and presented on MHC class I molecules by antigen-presenting cells, where it binds to the H-2Kᵇ allele in mouse models. This complex engages with specific T-cell receptors on CD8⁺ cytotoxic T-lymphocytes, leading to T-cell activation, proliferation, and the release of cytotoxic molecules such as perforin and granzymes, thereby initiating an antigen-specific immune response that targets cells presenting the epitope.

2.PRODUCT INDICATIONS

This peptide is indicated for immunological research applications, including in vitro and in vivo CTL activation assays, dendritic cell vaccination studies, tumor immunotherapy models, and as a positive control in T-cell-based functional assays. It is widely used in mouse models (e.g., C57BL/6) to investigate CD8⁺ T-cell biology, immune memory, and the efficacy of cancer vaccines.

3.CLINICAL EFFICACY OF PRODUCT

Ovalbumin(257-264) antigen peptide is a research reagent and is not approved for clinical use. However, it is instrumental in preclinical studies that have validated antigen-specific T-cell responses, supported the development of adoptive T-cell therapies and cancer vaccines, and contributed to the foundational knowledge enabling current immunotherapies, though it has no direct therapeutic efficacy in patients.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.