Palmitoyl Tripeptide-36

Palmitoyl Tripeptide-36

Palmitoyl Tripeptide-36

Palmitoyl Tripeptide-36

Palmitoyl Tripeptide-36

Palmitoyl Tripeptide-36 is a high-purity, synthetic lipopeptide engineered for premium anti-aging skincare. It features a specific three-amino acid sequence covalently linked to a palmitic acid (C16) chain. This lipid modification (palmitoylation) significantly enhances skin penetration, stability, and cellular targeting. The peptide is designed as a potent cell-communicating signal molecule that mimics natural biological processes. Its core function is to stimulate dermal fibroblasts to synthesize key extracellular matrix (ECM) components, including collagen, elastin, and hyaluronic acid, leading to visible improvements in skin firmness, elasticity, density, and wrinkle reduction. It is a cornerstone active for clinical-grade anti-aging formulations.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Palmitoyl Tripeptide-36
CAS NO.
/
Appearance
White to off-white lyophilized powder; odorless
Molecular Formula
C₄₇H₉₂N₁₀O₇
Molecular Weight
309.3 g/mol
Purity (RP-HPLC)
≥95.0%
Solubility
Soluble in DMSO, ethanol; slightly soluble in water; miscible in cosmetic oil phases
Endotoxin
<0.1 EU/mg
Biological Activity
Broad-spectrum antimicrobial peptide; inhibits Propionibacterium acnes, Staphylococcus aureus, Candida albicans, and Pseudomonas aeruginosa; reduces skin inflammation, controls oil secretion, and supports skin barrier function
Storage Conditions
Lyophilized powder: 2–8°C (short-term, 1 year); -20°C (long-term, 2 years); protect from moisture, light, and repeated freeze-thaw cycles
Stock Location
Stock in USA
MOQ
10g


1.MECHANISM OF ACTION

  • Receptor-Mediated Fibroblast Activation: The peptide's sequence is recognized by specific receptors on dermal fibroblasts. This binding activates intracellular MAPK/ERK and other signaling cascades, upregulating the expression of genes responsible for structural protein synthesis.

  • Upregulation of Structural Protein Production: This signaling leads to a significant increase in the production of Collagen Types I, III, and IV, Elastin, Fibronectin, and Glycosaminoglycans (GAGs). These proteins are essential for skin tensile strength, elasticity, and hydration.

  • Strengthening of the Dermal-Epidermal Junction (DEJ): It promotes the synthesis of DEJ-specific proteins (e.g., laminin, collagen IV), reinforcing the critical anchor between skin layers to improve resistance against sagging and enhance firmness.


    2.PRODUCT INDICATIONS

  • This peptide is specifically formulated for high-efficacy cosmetic products targeting advanced signs of aging:
    • Intensive Anti-Wrinkle & Anti-Sagging Serums/Creams: For deep wrinkles, loss of facial contour, and compromised skin elasticity.

    • Neck, Décolletage & Eye Contour Treatments: Specialized regimens for areas prone to fine lines and laxity.

    • Facial Lifting & Firming Formulations: To improve jawline definition and counteract gravity-induced sagging.

    • Premium Skin Renewal & Density-Boosting Products: For comprehensive restoration of a more youthful skin architecture and volume.


    3.CLINICAL EFFICACY OF PRODUCT

  • In Vitro Validation: Demonstrates a significant, dose-dependent stimulation of Collagen I synthesis (exceeding 120% increase) and other ECM proteins in human dermal fibroblast cultures.

  • Clinical Instrumental Measurements: Studies show a marked improvement in skin firmness (over 18% increase via cutometry) and enhanced elasticity (over 12% improvement) after 28-56 days of topical application.

  • Visual & Imaging Results: High-resolution 3D skin imaging confirms a reduction in wrinkle volume and depth (up to 20%). Expert grader assessment shows visible improvement in skin smoothness, tightness, and overall radiance.

  • Consumer-Perceived Benefits: High participant satisfaction scores for improved skin firmness, reduced appearance of sagging, and a more revitalized, youthful look.

  • 4.Certificate

      GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

      Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


      We prioritize:

      1.A rigorous quality management system

      2.Batch traceability and stability data

      3.Professional laboratory testing and validation

      4.Compliance with international trade standards


      Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

      5.DELIVERY & SHIPPING

      We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

      Professional and Secure Packaging

      Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

      We can also customize packaging according to customer needs.

      Shipping Methods 

      Main Method: International Air Freight

      We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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      Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

      We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


      Hot Tags: Pentapeptide-25, Anti-aging peptide, Collagen booster, Skin firming, Wrinkle reducer, Cosmetic ingredient, Peptide synthesis, Skincare, CAS 1000313-64-36, Synthetic peptide, Dermal repair, Extracellular matrix, Fibroblast activation, Topical serum, Cosmetic research, High purity peptide, Supplier, Manufacturer, Bulk order, Cosmetic raw materialResearch peptide, Pharmaceutical


      If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:852 7084 6510

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