Peptide YY (13-36) (canine, mouse, porcine, rat) CAS NO.86895-09-2
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Peptide YY (13-36) (canine, mouse, porcine, rat) |
| CAS NO. | 86895-09-2 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C135H209N41O38 |
| Molecular Weight | 3014.4g/mol |
| Purity (RP-HPLC) | ≥ 95.0% |
| Solubility | Soluble in water or aqueous buffers. For best results, prepare a stock solution in sterile water or PBS and aliquot to avoid repeated freeze-thaw cycles. |
| Endotoxin | < 1.0 EU/mg (Typical for research-grade peptides) |
| Biological Activity | Exhibits biological activity consistent with the PYY (13-36) fragment. Specific activity may vary depending on the assay system and experimental conditions. |
| Storage Conditions | Store lyophilized powder at -20°C or below. For long-term storage, keep at -80°C. Protect from light and moisture. Reconstituted solutions should be stored at -20°C or -80°C in single-use aliquots. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The mechanism of action of Peptide YY (13-36) involves its selective high-affinity binding to the Y2 receptor subtype. Unlike the full-length PYY (1-36), which binds to multiple Y receptor subtypes, this truncated form acts as a selective Y2 receptor agonist. Activation of presynaptic Y2 receptors in the hypothalamus leads to the inhibition of neuropeptide Y (NPY) release, which in turn suppresses appetite and reduces food intake by modulating central feeding circuits.
2.PRODUCT INDICATIONS
This product is indicated for use in scientific research focused on metabolic disorders, particularly obesity and diabetes. It is utilized to investigate the role of gut hormones in satiety signaling, the pathophysiology of eating disorders, and the development of therapeutic strategies aimed at modulating energy balance through the Y2 receptor pathway.
3.CLINICAL EFFICACY OF PRODUCT
In clinical and preclinical studies, administration of Peptide YY (13-36) has demonstrated significant efficacy in reducing caloric intake and promoting weight loss. It has been shown to decrease subjective hunger scores in human subjects and to induce sustained anorectic effects, making it a promising candidate for anti-obesity therapeutics by mimicking the natural postprandial satiety signal.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
