Name: Peptide YY (13-36) CAS 86895-09-2 for Canine & Rodents
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Peptide YY (13-36) (canine, mouse, porcine, rat) CAS NO.86895-09-2

Peptide YY (13-36) is a truncated form of the endogenous gut hormone Peptide YY (PYY), which is primarily secreted by enteroendocrine L-cells in the distal ileum and colon in response to food intake. This specific fragment is a key research tool used to study the physiological roles of PYY in appetite regulation, energy homeostasis, and gastrointestinal function, particularly focusing on its selective receptor interactions and metabolic effects.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Peptide YY (13-36) (canine, mouse, porcine, rat)
CAS NO.	86895-09-2
Appearance	White to off-white lyophilized powder
Molecular Formula	C135H209N41O38
Molecular Weight	3014.4g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water or aqueous buffers. For best results, prepare a stock solution in sterile water or PBS and aliquot to avoid repeated freeze-thaw cycles.
Endotoxin	< 1.0 EU/mg (Typical for research-grade peptides)
Biological Activity	Exhibits biological activity consistent with the PYY (13-36) fragment. Specific activity may vary depending on the assay system and experimental conditions.
Storage Conditions	Store lyophilized powder at -20°C or below. For long-term storage, keep at -80°C. Protect from light and moisture. Reconstituted solutions should be stored at -20°C or -80°C in single-use aliquots.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

The mechanism of action of Peptide YY (13-36) involves its selective high-affinity binding to the Y2 receptor subtype. Unlike the full-length PYY (1-36), which binds to multiple Y receptor subtypes, this truncated form acts as a selective Y2 receptor agonist. Activation of presynaptic Y2 receptors in the hypothalamus leads to the inhibition of neuropeptide Y (NPY) release, which in turn suppresses appetite and reduces food intake by modulating central feeding circuits.

2.PRODUCT INDICATIONS

This product is indicated for use in scientific research focused on metabolic disorders, particularly obesity and diabetes. It is utilized to investigate the role of gut hormones in satiety signaling, the pathophysiology of eating disorders, and the development of therapeutic strategies aimed at modulating energy balance through the Y2 receptor pathway.

3.CLINICAL EFFICACY OF PRODUCT

In clinical and preclinical studies, administration of Peptide YY (13-36) has demonstrated significant efficacy in reducing caloric intake and promoting weight loss. It has been shown to decrease subjective hunger scores in human subjects and to induce sustained anorectic effects, making it a promising candidate for anti-obesity therapeutics by mimicking the natural postprandial satiety signal.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
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Shipping Methods
Main Method: International Air Freight

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