Prepro-Atrial Natriuretic Factor (56-92) (human)
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Prepro‑Atrial Natriuretic Factor (56‑92) (human) |
| CAS NO. | |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C173H270N44O57 |
| Amino Acid Sequence | SLRRSSCFGGRMDRIGAQSGLGCNSFRY (human ANF prepro‑region residues 56‑92; contains intramolecular disulfide bond) |
| Molecular Weight | 3878.3g/mol |
| Purity (RP-HPLC) | ≥95.0% (customizable to ≥98.0%) |
| Solubility | Soluble in water, dilute acetic acid, or PBS (pH 7.0‑7.4) |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Precursor‑derived fragment of atrial natriuretic peptide; used in cardiovascular research, hormone processing studies, and receptor‑binding assays. |
| Storage Conditions | Store at –20°C (lyophilized) or –80°C (solution). Protect from light and repeated freeze‑thaw cycles. |
| Stock Location | Stock in USA |
| MOQ | 1mg |
1.MECHANISM OF ACTION
This peptide corresponds to a segment of the prepro‑ANF molecule and can be processed to generate biologically active natriuretic peptides. It interacts with natriuretic peptide receptors (e.g., NPR‑A), activating cyclic GMP signaling pathways that promote vasodilation, natriuresis, and diuresis, thereby contributing to blood pressure and volume homeostasis.
2.PRODUCT INDICATIONS
Prepro‑ANF (56‑92) (human) is employed in cardiovascular and endocrine research to investigate ANF biosynthesis, processing, and receptor‑mediated signaling. It is also used in assays studying fluid‑electrolyte balance, hypertension models, and the development of diagnostic or therapeutic agents targeting the natriuretic peptide system.
3.CLINICAL EFFICACY OF PRODUCT
As a research tool, this peptide is not intended for direct clinical application. However, it provides a critical reagent for elucidating the physiological and pathophysiological roles of ANF, supporting translational studies aimed at novel therapies for heart failure, hypertension, and renal disorders..
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
