Name: High-Purity Pulegone (CAS 89-82-7) for Fragrance & Flavor
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Pulegone/(+)-Pulegone CAS NO.89-82-7

Pulegone, specifically the (+)-Pulegone enantiomer, is a naturally occurring monoterpene ketone primarily extracted from mint family plants like peppermint and pennyroyal. It is characterized by a strong, refreshing minty and slightly camphoraceous aroma, making it a high-value intermediate and active ingredient. This product is supplied as a high-purity liquid, targeting industries that require natural mint flavorants, fragrance enhancers, or botanical active ingredients for R&D and formulation. Its key selling points include its natural origin, versatile application range from food flavors to biocides, and its studied biological activities, though it requires careful handling due to potency and regulatory limits in certain applications.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Pulegone/(+)-Pulegone
CAS NO.	89-82-7
Appearance	Colorless to pale yellow clear liquid
Molecular Formula	C10H16O
Molecular Weight	152.23 g/mol
Purity (RP-HPLC)	≥ 98.0%
Solubility	Slightly soluble in water; soluble in ethanol, ether, and most organic solvents
Endotoxin	/
Biological Activity	Exhibits insecticidal, repellent, and antimicrobial activities; acts as a flavoring and fragrance agent; potential neurotoxic effects at high doses
Storage Conditions	Store in a cool, dry, well-ventilated place away from light and heat; keep container tightly closed
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

The biological activity of (+)-Pulegone is attributed to its interaction with multiple cellular pathways. It functions as a modulator of transient receptor potential (TRP) channels, specifically activating TRPM8 to produce a cooling sensation and TRPA1 for irritant/repellent effects, which underlies its use in sensory products and pest control. On a molecular level, it exhibits anti-inflammatory properties by inhibiting key signaling pathways such as NF-κB and MAPK, reducing the production of pro-inflammatory cytokines like IL-1β and TNF-α. Additionally, it interferes with cyclooxygenase (COX) and lipoxygenase (LOX) enzymes, contributing to its analgesic and anti-histaminic effects, while its antimicrobial action helps in preserving formulations and enhancing functional benefits.

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2.PRODUCT INDICATIONS

This product is industrially indicated as a key raw material for creating mint flavors in food and beverages, including confectionery, gums, and oral care products, where it provides a natural cooling note. In the cosmetic and personal care sector, it serves as a fragrance ingredient in perfumes, soaps, and lotions, and is incorporated into topical balms for its soothing and cooling sensations. For agrochemical and functional applications, it is used in the formulation of natural insect repellents, eco-friendly pesticides, and animal repellents, leveraging its strong aroma and irritant properties. It is also supplied as a reference standard and intermediate for pharmaceutical research into anti-inflammatory and antimicrobial agents.

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3.CLINICAL EFFICACY OF PRODUCT

While not a finished pharmaceutical, preclinical studies on pulegone-containing extracts (e.g., peppermint oil) demonstrate efficacy in alleviating symptoms of irritable bowel syndrome (IBS), including abdominal pain and bloating, through its antispasmodic action on smooth muscle. Topical formulations have shown potential in reducing inflammation and itching in models of atopic dermatitis by suppressing mast cell activation and IgE levels. It is important to note that clinical use is constrained by safety profiles; high doses have been associated with hepatotoxicity and nephrotoxicity in animal studies, so commercial applications strictly adhere to regulatory limits (e.g., EFSA guidelines) to ensure consumer safety in flavor and fragrance uses.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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