Pulsatilloside E CAS NO.366814-43-9
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Pulsatilloside E |
| CAS NO. | 366814-43-9 |
| Appearance | White crystalline powder |
| Molecular Formula | C65H106O31 |
| Molecular Weight | 1383.52g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in Methanol, Acetonitrile, Ethanol; insoluble in Petroleum ether |
| Endotoxin | < 10 EU/mg |
| Biological Activity | Triterpenoid saponin isolated from Pulsatilla chinensis. Exhibits anti-tumor, anti-inflammatory, anti-viral, and anti-bacterial activities; used for content determination and pharmacological screening. |
| Storage Conditions | Store at 2-8°C, protected from light and moisture. Keep container tightly sealed. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Pulsatilloside E exerts its therapeutic effects through multi-target interactions, primarily by modulating key signaling pathways involved in inflammation and cell survival, such as inhibiting the NF-κB pathway to reduce the expression of pro-inflammatory cytokines like TNF-α and IL-6. It demonstrates significant antimicrobial activity by disrupting the cell membrane integrity of various bacteria and fungi, leading to cytoplasmic leakage and cell death, while also inducing apoptosis in cancer cells through the mitochondrial pathway by regulating Bcl-2 family proteins and activating caspase cascades. Additionally, the compound exhibits antioxidant capabilities by scavenging free radicals and enhancing the activity of endogenous antioxidant enzymes, thereby protecting cells from oxidative stress-induced damage and supporting overall cellular homeostasis.
2.PRODUCT INDICATIONS
Pulsatilloside E is indicated for non-clinical research and pharmaceutical development applications focusing on infectious diseases, oncology, and inflammatory disorders, where it is utilized to evaluate the efficacy of novel antimicrobial agents and investigate the mechanisms of drug resistance in pathogenic microbes. Researchers employ this compound to study the chemopreventive effects against various carcinomas, including colorectal and liver cancers, often using it as a benchmark for screening pro-apoptotic agents in cellular models. Furthermore, it serves as a primary analytical standard for manufacturers developing herbal medicines and nutraceuticals derived from Pulsatilla chinensis, catering to professionals in drug discovery, pharmacognosy, and the standardization of botanical products aimed at treating amoebic dysentery and other infections.
3.CLINICAL EFFICACY OF PRODUCT
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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