Rebaudioside M CAS NO.1220616-44-3

Rebaudioside M CAS NO.1220616-44-3

Rebaudioside M  CAS NO.1220616-44-3

Rebaudioside M CAS NO.1220616-44-3

Rebaudioside M CAS NO.1220616-44-3

Rebaudioside M (CAS NO. 1220616-44-3) is a high-purity, single-component steviol glycoside isolated from the stevia plant. It is one of the sweetest and most sensorially advanced steviol glycosides known, estimated to be 200-350 times sweeter than sucrose. Compared to earlier-generation stevia sweeteners like Rebaudioside A (Reb A), Reb M offers a cleaner, more sugar-like taste profile with significantly reduced bitterness and licorice aftertaste. It is ideal for zero-calorie, natural product formulation in beverages, foods, and pharmaceuticals, driving the next wave of sugar reduction. It is supplied as a high-purity white to off-white powder.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Rebaudioside M
CAS NO.
1220616-44-3
Appearance
White to off-white solid powder
Molecular Formula
C₅₆H₉₀O₃₃
Molecular Weight
1291.29 g/mol
Purity (RP-HPLC)
≥95.0%
Solubility
Soluble in DMSO (≥30 mg/mL, up to 100 mg/mL with sonication); slightly soluble in water; soluble in methanol/ethanol
Endotoxin
<0.1 EU/mg
Biological Activity
Agonist of human TAS1R2/TAS1R3 sweet taste receptor (EC₅₀ = 29.54 µM); relative sweetness potency: 200–350 times that of sucrose; non-caloric natural sweetener
Storage Conditions
-20°C (long-term, sealed, protected from light and moisture); short-term: 2–8°C; avoid repeated freeze-thaw cycles
Stock Location
Stock in USA
MOQ
10g


1.MECHANISM OF ACTION

  • For Potential Health Effects (based on steviol glycoside research):
    1. Blood Glucose Regulation: Like other steviol glycosides, it may have a neutral or beneficial effect on blood glucose and insulin levels, making it suitable for diabetics.

    2. Anti-hypertensive Potential: Some steviol glycosides exhibit blood pressure-lowering effects, potentially via vasodilation and diuretic actions.

    3. General Safety & Non-Cariogenic: Does not promote tooth decay (non-cariogenic) and is generally recognized as safe (GRAS) in many jurisdictions.

     

  • 2.PRODUCT INDICATIONS

  • Food & Beverage Industry: As a premium, high-intensity natural sweetener in zero- and reduced-calorie products, especially in beverages (soft drinks, juices, teas), dairy, confectionery, and baked goods where a clean sugar-like taste is critical.

  • Nutraceuticals & Dietary Supplements: For sweetening powders, tablets, and liquids targeting diabetic, weight management, and ketogenic consumers.

  • Pharmaceuticals: As an excipient to improve the palatability of syrups, suspensions, and chewable tablets without affecting blood sugar.

  • Tabletop Sweeteners: In blended or single-ingredient packet/bulk formats for consumer use.

  • eases due to its antioxidant, anti-inflammatory, and potential AChE inhibitory activities.

3.CLINICAL EFFICACY OF PRODUCT

  • Sensory Efficacy: Blind taste tests consistently show that Reb M achieves a taste profile closer to sugar than Reb A, with dramatically reduced bitterness and aftertaste. This is its primary and proven advantage.

  • Zero Glycemic Impact: Clinical studies on steviol glycosides confirm they do not raise blood glucose or insulin levels, making them safe and suitable for diabetics. Reb M shares this property.

  • Safety & Regulatory Status: Extensively studied toxicology data supports its safety. It has achieved GRAS (Generally Recognized as Safe) status from the FDA for use in foods and beverages, and is approved in numerous other countries (e.g., EU, Japan, Brazil).

  • Commercial Validation: Major global food and beverage companies are actively formulating with Reb M to create better-tasting reduced-sugar products, signaling strong market confidence in its performance.


  • 4.Certificate

    • GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

    Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


    We prioritize:

    1.A rigorous quality management system

    2.Batch traceability and stability data

    3.Professional laboratory testing and validation

    4.Compliance with international trade standards


    Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

    5.DELIVERY & SHIPPING

    We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

    Professional and Secure Packaging

    Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

    We can also customize packaging according to customer needs.

    Shipping Methods 

    Main Method: International Air Freight

    We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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    Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

    We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


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    If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:852 7084 6510

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