Renoguanylin (eel)
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Renoguanylin (eel) |
| CAS NO. | / |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C66H102N16O22S4 |
| Molecular Weight | 1599.9g/mol |
| Purity (RP-HPLC) | ≥ 95.0% |
| Solubility | Soluble in water, dilute acetic acid, PBS (pH 7-8) |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Eel kidney guanosine peptide; belonging to the guanosine peptide family, it can activate guanylate cyclase receptors and participate in osmotic pressure regulation and ion balance. It is a tool peptide for studying osmotic regulation and kidney function in fish. |
| Storage Conditions | Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Renoguanylin (eel) functions as an endogenous ligand that binds to and activates guanylate cyclase-C (GC-C) receptors in fish tissues, particularly in the kidney and intestine. This binding stimulates the intracellular catalytic domain of GC-C, leading to the conversion of GTP to cyclic GMP (cGMP). The elevated cGMP levels activate downstream effectors, including protein kinase G (PKG), which phosphorylates ion channels and transporters involved in electrolyte transport. In eels and other teleost fish, this signaling cascade primarily regulates sodium and chloride ion transport across epithelial membranes, contributing to osmoregulation in both freshwater and marine environments. The peptide's activity is dependent on proper disulfide bond formation, which maintains its three-dimensional structure and receptor-binding affinity.
2.PRODUCT INDICATIONS
3.CLINICAL EFFICACY OF PRODUCT
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
