Sarafotoxin 6c CAS NO.121695-87-2
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Sarafotoxin 6c |
| CAS NO. | 121695-87-2 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C103H147N27O37S5 |
| Molecular Weight | 2515.g/mol |
| Purity (RP-HPLC) | ≥ 95.0% |
| Solubility | Soluble in water, PBS, or dilute acetic acid. It is recommended to dissolve in sterile water or buffer to prepare stock solutions for biological assays. |
| Endotoxin | < 1.0 EU/mg (Typical for research-grade peptides) |
| Biological Activity | Sarafotoxin 6c is a potent vasoconstrictor and bronchoconstrictor. It acts as a selective agonist for the endothelin B (ETB) receptor, making it a valuable tool for studying endothelin receptor pharmacology and vascular physiology. |
| Storage Conditions | Store at -20°C or lower. For long-term storage, keep desiccated at -20°C. Upon reconstitution, aliquot and store at -20°C to avoid repeated freeze-thaw cycles. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Sarafotoxin 6c exerts its effects by selectively binding to and activating the endothelin B (ETB) receptor, triggering downstream signaling pathways that lead to vasoconstriction . This mechanism is independent of endothelial integrity, as it induces contraction in both intact and denuded vascular preparations, highlighting its direct action on smooth muscle cells.
2.PRODUCT INDICATIONS
This product is indicated for use in research settings to explore ETB receptor pharmacology, including studies on vascular tone regulation, receptor subtype specificity, and the development of experimental models for cardiovascular diseases. It serves as a critical tool for validating ETB receptor function and for screening potential antagonists or modulators of the endothelin system.
3.CLINICAL EFFICACY OF PRODUCT
Sarafotoxin 6c is intended for research purposes only and is not approved for diagnostic or therapeutic use in humans. Its clinical relevance is confined to its utility as a biochemical reagent in preclinical studies investigating vascular physiology and receptor pharmacology.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
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