tBuO-Ste-Glu(AEEA-AEEA-OH)OtBu CAS NO.1118767-16-0

tBuO-Ste-Glu(AEEA-AEEA-OH)OtBu CAS NO.1118767-16-0

tBuO-Ste-Glu(AEEA-AEEA-OH)OtBu  CAS NO.1118767-16-0
tBuO-Ste-Glu(AEEA-AEEA-OH)OtBu  CAS NO.1118767-16-0
tBuO-Ste-Glu(AEEA-AEEA-OH)OtBu  CAS NO.1118767-16-0
tBuO-Ste-Glu(AEEA-AEEA-OH)OtBu  CAS NO.1118767-16-0

tBuO-Ste-Glu(AEEA-AEEA-OH)OtBu CAS NO.1118767-16-0

tBuO-Ste-Glu(AEEA-AEEA-OH)OtBu CAS NO.1118767-16-0

Abstract: tBuO-Ste-Glu(AEEA-AEEA-OH)OtBu is a white, powdery organic compound used in peptide synthesis. Featuring tert-butoxycarbonyl (tBuO) and glutamic acid derivatives, it serves as a key intermediate in drug development due to its stability and reactivity.

TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
tBuO-Ste-Glu(AEEA-AEEA-OH)OtBu
CAS NO.
1118767-16-0
Appearance
Off-white to pale yellow waxy solid or amorphous powder; free from visible impurities.
Molecular Formula
C₃₉H₇₅N₃O₁₂
Molecular Weight
786.03 g/mol
Purity (RP-HPLC)
≥95%
Solubility

  • Soluble in organic solvents: ≥ 25 mg/mL in DMSO, ≥ 15 mg/mL in methanol/ethanol, ≥ 10 mg/mL in dichloromethane
Endotoxin< 1.0 EU/mg
Biological Activity
 used in the research and development of peptide-drug conjugation (PDC), targeted drug delivery systems
Storage Conditions
Store at 2-8℃ in a tightly sealed container, protected from light, moisture, and oxidants.
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

This compound acts as a sophisticated chemical linker and building block for constructing advanced bioconjugates, rather than having direct biological activity. Its mechanism centers on its protected functional groups, which allow for sequential, orthogonal chemical reactions.


2.PRODUCT INDICATIONS

  • Lipopeptide Vaccine Development – Constructing lipid-antigen conjugates for enhanced immunogenicity and delivery.
  • Antibody-Drug Conjugate (ADC) Linker Systems – Building stable, cleavable, or non-cleavable linkers for targeted cancer therapies.
  • Therapeutic Peptide Lipidation – Enhancing the stability, half-life, and membrane permeability of peptide drugs.
  • Nanocarrier Functionalization – Surface modification of liposomes, lipid nanoparticles (LNPs), or micelles for active targeting.
  • Prodrug Synthesis – Creating lipidated prodrugs with improved pharmacokinetics and tissue-specific release.

  • 3.CLINICAL EFFICACY OF PRODUCT

    As a chemical building block, tBuO-Ste-Glu(AEEA-AEEA-OH)OtBu itself is not a therapeutic agent. However, its strategic incorporation into bioconjugates directly contributes to their clinical efficacy by addressing key pharmacological challenges. Conjugates utilizing this scaffold demonstrate: Enhanced Pharmacokinetics – The lipid chain (Ste) promotes binding to serum albumin, extending circulation half-life.


    4.DELIVERY & SHIPPING

    We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.


    Professional and Secure Packaging
    Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
    We can also customize packaging according to customer needs.


    Shipping Methods 
    Main Method: International Air Freight

    We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.


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