Teduglutide CAS NO.197922-42-2
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Teduglutide |
| CAS NO. | 197922-42-2 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C₁₆₄H₂₅₂N₄₄O₅₅S |
| Molecular Weight | 3752.43 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in water for injection; reconstitute with sterile water or specified diluent before use |
| Endotoxin | < 1 EU/mg (pharmaceutical grade) |
| Biological Activity | Potent GLP-2 receptor agonist; promotes intestinal mucosal growth, enhances nutrient absorption, and supports intestinal adaptation in short bowel syndrome patients |
| Storage Conditions | Store at 2–8°C, protected from light; avoid freezing. Reconstituted solution stable for limited time per manufacturer guidelines |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Teduglutide works by mimicking the action of endogenous GLP-2, binding to and activating GLP-2 receptors located on enteroendocrine cells, subepithelial myofibroblasts, and enteric neurons within the intestinal mucosa. This activation triggers a cascade of trophic effects, including the stimulation of crypt cell proliferation, inhibition of enterocyte apoptosis, and an increase in villus height and crypt depth. The result is a substantial expansion of the intestinal absorptive surface area, accompanied by enhanced local blood flow and reduced gastric acid secretion, which collectively optimize the gut's capacity to absorb water, electrolytes, and macronutrients.
2.PRODUCT INDICATIONS
3.CLINICAL EFFICACY OF PRODUCT
In Phase 3 clinical trials (STEPS, TED trials), Teduglutide demonstrated significant efficacy in SBS patients. Treatment resulted in a clinically meaningful reduction (≥20%) in weekly parenteral support volume in 63% of patients versus 30% with placebo. Many patients achieved enteral autonomy (full weaning from PS). Efficacy was sustained with long-term use, improving quality of life and nutritional markers. The most common adverse events were gastrointestinal-related (abdominal pain, nausea) and generally manageable.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: Mosloflavone #5Hydroxy67dimethoxyflavone #Flavonoid #Antiviral #AntiInflammatory #AntiBiofilm #NFkBInhibitor #EnterovirusInhibitor #InfluenzaResearch #DrugDiscovery #NaturalProduct #PharmacologyResearch #BiomedicalResearch #Phytochemical
If you have any product requirements, please send an email to:sales@huanqiukeji9.com;whatsapp:85244219157
