Undecenyl Dipeptide-16

Undecenyl Dipeptide-16

Undecenyl Dipeptide-16

Undecenyl Dipeptide-16

Undecenyl Dipeptide-16

Undecenyl Dipeptide-16 is a specialized lipopeptide synthesized by conjugating a dipeptide sequence with an undecenyl fatty acid chain. This structural modification enhances its lipid solubility and skin penetration capabilities. It is designed for targeted cosmetic applications, where its primary role is to improve skin hydration and barrier function and may be associated with specific bioactive signaling pathways, making it a valuable ingredient in advanced moisturizing and restorative skincare formulations.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Undecenyl Dipeptide-16
CAS NO.
/
Appearance
White to off-white lyophilized powder
Molecular Formula
C₂₁H₃₅N₃O₅
Molecular Weight
 421.5 g/mol
Purity (RP-HPLC)
≥ 95.0%
Solubility

Soluble in ethanol, propylene glycol, cosmetic oils; slightly soluble in water (solubilizers recommended)

Endotoxin< 1.0 EU/mg
Biological Activity
Melanogenesis inhibitor: MC1R antagonist blocking α-MSH binding; downregulates MITF, tyrosinase, TRP-1/2; anti-inflammatory (UVB-induced); skin brightening; photoprotective
Storage Conditions
Store at 2-8°C in cool, dry, dark place; avoid extreme temperatures and moisture
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

The mechanism of action for Undecenyl Dipeptide-16 is likely tied to its dipeptide sequence, which is designed to mimic or regulate specific biological processes, coupled with the penetration-enhancing properties of the undecenyl chain.

  1. Biomimetic Signaling: The dipeptide sequence may act as a signal peptide, designed to interact with specific receptors on skin cells (e.g., keratinocytes or fibroblasts). This interaction could trigger beneficial cellular responses, such as upregulating the synthesis of proteins or lipids essential for the skin barrier.

  2. Barrier Reinforcement and Hydration: A primary proposed function is the stimulation of key components of the skin's Natural Moisturizing Factor (NMF) or the synthesis of barrier lipids (like ceramides) in the stratum corneum. This helps to reinforce the skin's barrier, reducing Trans-Epidermal Water Loss (TEWL) and improving hydration levels.

  3. Enhanced Delivery: The undecenyl (C11) lipid chain improves the peptide's affinity for the skin's lipid bilayers, facilitating deeper delivery and retention of the active dipeptide signal within the epidermis.


2.PRODUCT INDICATIONS

This product is indicated for cosmetic science and the formulation of high-performance skincare focused on hydration, barrier repair, and skin conditioning. Key applications include:

  • As an active ingredient in intensive moisturizers, barrier repair creams, and hydrating serums for dry, dehydrated, or sensitive skin.

  • In formulations designed to strengthen the skin's moisture barrier and improve resilience against environmental stressors.

  • For products targeting skin conditioning and smoothness, contributing to a supple and plump complexion.

  • As a supportive ingredient in anti-aging regimens where robust hydration and barrier integrity are foundational for skin health.

  • In post-procedure soothing treatments to aid in skin recovery and hydration.


3.CLINICAL EFFICACY OF PRODUCT

While specific large-scale clinical data on Undecenyl Dipeptide-16 may be more limited compared to some established peptides, its efficacy is supported by:
  • In-vitro data demonstrating its ability to stimulate the production of NMF components or barrier lipids in skin cell models.

  • Formulation-based clinical studies showing that products containing this ingredient lead to measurable improvements in skin hydration (via corneometer) and barrier function (via TEWL measurements).

  • Subjective consumer assessments reporting improvements in skin softness, smoothness, and a reduction in tightness or dryness with regular use.

It is validated as an effective hydrating and barrier-supporting active in cosmetic formulations.


4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods 
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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