VIP, guinea pig CAS NO.96886-24-7
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | VIP, guinea pig |
| CAS NO. | 96886-24-7 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C147H239N43O42S2 |
| Molecular Weight | 3344.93/mol |
| Purity (RP-HPLC) | ≥98% |
| Solubility | Soluble in water (≥10 mg/mL), dilute acetic acid, or 0.1M HCl |
| Endotoxin | ≤1.0 EU/mg |
| Biological Activity | Potent vasodilator and neurotransmitter; binds to VPAC1 and VPAC2 receptors, regulating smooth muscle relaxation, vasodilation, and immune function. |
| Storage Conditions | Store at -20°C to -80°C in a dry, dark environment; avoid repeated freeze-thaw cycles. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
This peptide exerts its broad physiological effects by binding to and activating two class B G protein-coupled receptors, VPAC1 and VPAC2, with high affinity. Receptor activation primarily stimulates the Gs protein pathway, leading to activation of adenylate cyclase, a significant increase in intracellular cyclic AMP (cAMP) levels, and subsequent activation of protein kinase A (PKA).
2.PRODUCT INDICATIONS
3.CLINICAL EFFICACY OF PRODUCT
VIP, guinea pig itself is not a human therapeutic but is a cornerstone research reagent. Its "efficacy" is proven in preclinical guinea pig models, which are gold standards for studying human-like airway and smooth muscle physiology. Research using this species-specific peptide has been fundamental in elucidating VIP's role as a potent bronchodilator and anti-inflammatory agent in the lungs, directly contributing to the validation of the VIP/VPAC receptor pathway as a therapeutic target for respiratory diseases like asthma and chronic obstructive pulmonary disease (COPD).
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
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