Yamogenin CAS NO.512-06-1

Yamogenin CAS NO.512-06-1

Yamogenin CAS NO.512-06-1

Yamogenin CAS NO.512-06-1

Yamogenin CAS NO.512-06-1

Yamogenin is a steroidal sapogenin, a natural bioactive compound derived from certain plant species, notably Dioscorea (yam) and other members of the Dioscoreaceae family. It serves as a key precursor in the synthesis of various steroidal drugs and hormones. Yamogenin is primarily recognized for its potential role in pharmaceutical and nutraceutical applications, particularly in the production of corticosteroids, sex hormones, and other therapeutic steroids.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Yamogenin
CAS NO.
512-06-1
Appearance
White to off-white crystalline powder; solid
Molecular Formula
C₂₇H₄₂O₃
Molecular Weight
414.62–414.63 g/mol
Purity (RP-HPLC)
≥98%
Solubility
Soluble in chloroform, ethanol, DMSO; slightly soluble in pyridine; insoluble in water
Endotoxin
<0.1 EU/mg
Biological Activity
Antagonizes liver X receptor (LXR) activation; inhibits triglyceride accumulation; anti-hyperlipidemic agent
Storage Conditions
- Powder: -20°C (desiccated, protected from light) for 3 years; 4°C for 2 years
- Stock solutions: -80°C for 6 months; -20°C for 1 month (avoid repeated freeze-thaw cycles)
Stock Location
Stock in USA
MOQ
10g


1.MECHANISM OF ACTION

  • Yamogenin acts as a steroidal precursor that can be chemically or biotechnologically converted into valuable steroid intermediates, such as diosgenin derivatives. In biological systems, it may influence metabolic pathways by interacting with steroid receptors or modulating enzyme activities involved in steroidogenesis. Its structural similarity to endogenous steroids allows it to serve as a building block for synthesizing compounds with anti-inflammatory, hormonal, or metabolic regulatory effects.

  • 2.PRODUCT INDICATIONS

Yamogenin is indicated for use as a critical raw material in the pharmaceutical industry for the manufacture of steroid-based medications, including corticosteroids, contraceptives, and hormone replacement therapies. It is also utilized in nutraceutical formulations targeting hormonal balance, anti-inflammatory support, and metabolic health. Additionally, it finds applications in research and development for studying steroid biochemistry and drug discovery.

    3.CLINICAL EFFICACY OF PRODUCT

    While direct clinical trials on Yamogenin are limited, evidence from related steroidal sapogenins and their derivatives supports its potential in therapeutic contexts. Studies on compounds derived from Yamogenin show efficacy in reducing inflammation, managing hormonal disorders, and alleviating conditions like arthritis and menopausal symptoms. Its role as a precursor contributes to the production of clinically proven steroids, underscoring its importance in medicine and health supplements.

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